Portal Vein Thrombosis (PVT): Symptoms, Causes, and Treatment
Portal vein thrombosis treatment options Treatment greatly depends on the initial cause of the blood clot. For portal vein thrombosis, treatment recommendations will focus on dissolving the blood…
https://www.healthline.com/health/portal-vein-thrombosis
Portal vein thrombosis: When to treat and how? – Aditya M …
Portal vein thrombosis continues to be a complicated and difficult condition with significant morbidity and mortality. Outcomes are more severe in cirrhotic patients and those with malignancy. Although there has been some progress in understanding the pathophysiology and treatment options, there is still a lack of randomized clinical data to guide therapy. For the majority of individuals with acute PVT, anticoagulation is the preferred method of treatment, with fewer cases managed …
https://journals.sagepub.com/doi/full/10.1177/1358863X15611224
Anticoagulation for portal vein thrombosis: a quick …
Portal vein thrombosis can present in the acute or chronic setting in patients with or without cirrhosis The cornerstone of therapy is anticoagulation, which is mandatory where there is intestinal ischaemia or an underlying pro-coagulant condition
https://www.bsg.org.uk/clinical-articles-list/anticoagulation-for-portal-vein-thrombosis-a-quick-revision-aid/
Diagnosis, Development, and Treatment of Portal Vein …
Portal vein thrombosis unrelated to solid malignancy is common in patients with cirrhosis, but less frequently observed in patients without cirrhosis. Prompt diagnosis and management of acute symptomatic portal vein thrombosis are essential. Failure to detect and treat thromboses can result in mesenteric ischemia, chronic cavernous transformation, and complications of portal hypertension. In patients with cirrhosis, development of portal vein thrombosis is often insidious and remains …
https://pubmed.ncbi.nlm.nih.gov/30771355/
Controversies in the Management of Portal Vein Thrombosis …
Portal vein thrombosis (PVT) is frequently diagnosed in advanced‐stage liver cirrhosis, with a reported prevalence of 10 to 25% [1,2]. However, whether PVT directly affects the outcome of
https://www.mdpi.com/2077-0383/9/12/3916/pdf
Treatment of Hepatocellular Carcinoma With Portal Venous …
The natural history of hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) is dismal (approximately 2-4 mo), and PVTT is reportedly found in 10%-40% of HCC patients at diagnosis. According to the Barcelona Clinic Liver Cancer (BCLC) Staging System (which is the most widely adopted HCC management guideline), sorafenib is the standard of care for advanced HCC (i.e., BCLC stage C) and the presence of PVTT is included in this category. However, sorafenib treatment only …
https://pubmed.ncbi.nlm.nih.gov/26755886/
Newer Oral Anticoagulants in the Treatment of Acute Portal …
In contrast, most guidelines in the literature support the treatment of acute portal vein thrombosis (PVT) with low molecular weight heparin (LMWH) and vitamin K antagonists (VKA). Literature evaluating NOAC use in the treatment of acute portal vein thrombosis is sparse.
https://www.hindawi.com/journals/ijh/2018/8432781/
Portal Vein Thrombosis: Imaging the Spectrum of Disease …
Ultrasound imaging and interventional treatment of portal vein thrombosis. Ultrasound Clin 2013; 8:237–247 [Google Scholar] 10. Qi X, Han G, He C, et al. CT features of non-malignant portal vein thrombosis: a pictorial review. Clin Res Hepatol Gastroenterol 2012; 36:561–568 [Google Scholar] 11. Mori H, Hayashi K, Uetani M, Matsuoka Y, Iwao M, Maeda H. High-attenuation recent thrombus of …
https://www.ajronline.org/doi/10.2214/AJR.18.19548
The efficacy and safety of direct oral anticoagulants in …
Guidelines currently favor vitamin K antagonists or low-molecular-weight heparins for treatment of noncirrhotic portal vein thrombosis (ncPVT). Use of direct oral anticoagulants (DOACs) in PVT has been met with concern because of the lack of data. We conducted a retrospective study to investigate the efficacy and safety of DOACs for the treatment of ncPVT, and to compare them with standard …
https://ashpublications.org/bloodadvances/article/4/4/655/452520/The-efficacy-and-safety-of-direct-oral
Portal vein thrombosis | Radiology Reference Article …
Portal vein thrombosis may be seen in a variety of clinical contexts, and when acute can be a life-threatening condition. It is a major cause of non-cirrhotic presinusoidal portal hypertension.Portal vein thrombus may be either bland and/or malignant (i.e. tumor thrombus), and it is a critical finding in liver transplant candidates, as it precludes transplantation.
https://radiopaedia.org/articles/portal-vein-thrombosis